Recombinant Mouse Diaph1 Protein, Myc/DDK-tagged

• Cat.No.: Diaph1-2564M
• Product Overview: Purified recombinant protein of mouse full-length diaphanous related formin 1 (Diaph1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the formin family of proteins that play important roles in cytoskeletal rearragnement by nucleation of actin filaments. Mice lacking the encoded protein develop age-dependent myeloproliferative defects resembling human myeloproliferative syndrome and myelodysplastic syndromes. Trafficking of T lymphocytes to secondary lymphoid organs and egression of thymocytes from the thymus are impaired in these animals. Lack of the encoded protein in T lymphocytes and thymocytes also reduces chemotaxis. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Molecular Mass: 139.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Diaph1 diaphanous related formin 1 [ Mus musculus (house mouse) ]
• Official Symbol: Diaph1
• Synonyms: Diaph1; diaphanous related formin 1; Di; Drf; mDi; Dia1; Drf1; Diap1; p140m; p140mDia; D18Wsu154; D18Wsu154e; protein diaphanous homolog 1
• Gene ID: 13367
• mRNA Refseq: NM_007858
• Protein Refseq: NP_031884
• UniProt ID: O08808