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Recombinant Mouse Dnm2 Protein, Myc/DDK-tagged

Cat.No. : Dnm2-2619M
Product Overview : Purified recombinant protein of mouse full-length dynamin 2 (cDNA clone MGC:7779 IMAGE:3499181), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones. Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 51.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Dnm2 dynamin 2 [ Mus musculus (house mouse) ]
Official Symbol : Dnm2
Synonyms : DNM2; dynamin 2; dynamin-2; dynamin UDNM; Dyn2
Gene ID : 13430
mRNA Refseq : NM_007871
Protein Refseq : NP_031897
UniProt ID : P39054

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the relationship between DNM2 and β-actin? 11/10/2022

DNM2 interacts with β-actin.

What diseases is DNM2 primarily involved in? 03/14/2021

DNM2 is closely associated with the study of chronic heart failure and chronic progressive extraocular muscle paralysis in the elderly.

Where is DNM2 primarily expressed? 03/08/2021

DNM2 gene is widely expressed in various mammalian tissues.

What are the other homologous genes of DNM2? 03/03/2021

DNM1 and DNM3 are all homologs of DNM2.

What biological processes is DNM2 involved in? 11/24/2020

DNM2 is involved in the regulation of Golgi reticular system transport, mitochondrial fusion, cytoplasmic division and synaptic vesicle endocytosis.

What is the structure domain of DNM2? 11/21/2020

N-terminal GTPase structural domain, intermediate domain, PH structural domain, GTPase effector structural domain, and C-terminal proline- and arginine-rich domain.

Customer Reviews (3)

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Reviews
03/02/2023

    DNM2 proteins purchased are as advertised and the quality of the product is guaranteed.

    08/16/2022

      Excellent after-sales service, solving many experimental problems.

      03/12/2022

        The technician gave me a thorough introduction to the DNM2 protein so that I could understand its biochemical properties.

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