Recombinant Mouse DOCK8 Protein (561-730 aa), His-tagged

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Recombinant Mouse DOCK8 Protein (561-730 aa), His-tagged

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Cat.No. : DOCK8-2251M
Product Overview : Recombinant Mouse DOCK8 Protein (561-730 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial.
Description : Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Is involved in NK cell cytotoxicity controlling polarization of microtubule-organizing center (MTOC), and possibly regulating CCDC88B-mediated lytic granule transport to MTOC during cell killing.
Source : Yeast
Species : Mouse
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 21.2 kDa
Protein length : 561-730 aa
AA Sequence : RNLLYVYPQR LNFASKLASA RNITIKIQFM CGEDPSNAMP VIFGKSSGPE FLQEVYTAIT YHNKSPDFYE EVKIKLPAKL TVNHHLLFTF YHISCQQKQG ASGESLLGYS WLPILLNERL QTGSYCLPVA LEKLPPNYSI HSAEKVPLQN PPIKWAEGHK GVFNIEVQAV
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : Dock8 dedicator of cytokinesis 8 [ Mus musculus (house mouse) ]
Official Symbol : DOCK8
Synonyms : Dock8; AI461977; 1200017A24Rik; 5830472H07Rik; A130095G14Rik;
Gene ID : 76088
mRNA Refseq : NM_028785
Protein Refseq : NP_083061
UniProt ID : Q8C147

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