Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Mouse Dock8 Protein, Myc/DDK-tagged

Cat.No. : Dock8-2628M
Product Overview : Purified recombinant protein of mouse full-length dedicator of cytokinesis 8 (Dock8), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
  • Related Products
Description : Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4+ T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity controlling polarization of microtubule-organizing center (MTOC), and possibly regulating CCDC88B-mediated lytic granule transport to MTOC during cell killing.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 239.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Dock8 dedicator of cytokinesis 8 [ Mus musculus (house mouse) ]
Official Symbol : Dock8
Synonyms : Dock8; dedicator of cytokinesis 8; AI461977; 1200017A24Rik; 5830472H07Rik; A130095G14Rik; dedicator of cytokinesis protein 8
Gene ID : 76088
mRNA Refseq : NM_028785
Protein Refseq : NP_083061
UniProt ID : Q8C147

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All Dock8 Products

Required fields are marked with *

My Review for All Dock8 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends