Recombinant Mouse Dusp6 Protein, Myc/DDK-tagged

• Cat.No.: Dusp6-2691M
• Product Overview: Purified recombinant protein of mouse full-length dual specificity phosphatase 6 (Dusp6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Inactivates MAP kinases. Has a specificity for the ERK family. Plays an important role in alleviating acute postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia. Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 42.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dusp6 dual specificity phosphatase 6 [ Mus musculus (house mouse) ]
• Official Symbol: Dusp6
• Synonyms: DUSP6; dual specificity phosphatase 6; dual specificity protein phosphatase 6; MAP kinase phosphatase 3; mitogen-activated protein kinase phosphatase 3; MKP3; MKP-3; PYST1; 1300019I03Rik; MGC98540
• Gene ID: 67603
• mRNA Refseq: NM_026268
• Protein Refseq: NP_080544
• UniProt ID: Q9DBB1