Recombinant Mouse Dync2i2 Protein, Myc/DDK-tagged

• Cat.No.: Dync2i2-6977M
• Product Overview: Purified recombinant protein of Mouse WD repeat domain 34 (Wdr34), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I2 plays a major role in retrograde ciliary protein trafficking and in ciliogenesis. Required also to maintain a functional transition zone.
• Molecular Mass: 46 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dync2i2 dynein 2 intermediate chain 2 [ Mus musculus (house mouse) ]
• Official Symbol: Dync2i2
• Synonyms: Dync2i2; dynein 2 intermediate chain 2; Wdr34; 3200002I06Rik; cytoplasmic dynein 2 intermediate chain 2; WD repeat domain 34; WD repeat-containing protein 34
• Gene ID: 71820
• mRNA Refseq: NM_001008498
• Protein Refseq: NP_001008498
• UniProt ID: Q5U4F6