Recombinant Mouse Fgf2 Protein

• Cat.No.: Fgf2-13M
• Product Overview: Recombinant mouse FGF-2 (bFGF) protein without tag was expressed in E. coli.
  Animal-free (AOF) and carrier protein-free.
  Mass spectrometry: single species with expected mass.
  Recovery from stock vial: >95%

Specification

• Description: Enables growth factor activity. Involved in stem cell development. Acts upstream of or within several processes, including animal organ development; positive regulation of macromolecule metabolic process; and positive regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; corneal neovascularization; diabetic neuropathy; gastric ulcer; and impotence. Orthologous to human FGF2 (fibroblast growth factor 2).
• Source: E. coli
• Species: Mouse
• Molecular Mass: 16 kDa
• Endotoxin: <0.005 EU/μg protein (below level of detection)
• Applications: Differentiation of human pluripotent Stem cells towards extra-embryonic endoderm, mesenchymal, neural lineages, and chondrocytes
• Storage: Prepare single use aliquots, add carrier protein if desired, store frozen at -20 or -80 centigrade
• Storage Buffer: Frozen in PBS

Gene Information

• Gene Name: Fgf2 fibroblast growth factor 2 [ Mus musculus (house mouse) ]
• Official Symbol: Fgf2
• Synonyms: FGF2; fibroblast growth factor 2; BFGF; FGF-2; HBGF-2; fibroblast growth factor 2; basic fibroblast growth factor; fibroblast growth factor 2 (basic); heparin-binding growth factor 2
• Gene ID: 14173
• mRNA Refseq: NM_008006
• Protein Refseq: NP_032032
• UniProt ID: P15655

Reviews

07/14/2022

The technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.

02/04/2022

The purchased protein is suitable for WB experiments and I am satisfied with the results.

Q&As

What is the biological function of FGF2?

FGF2 promotes cell migration and angiogenesis and regulates bone homeostatic balance.

Where is FGF2 mainly expressed?

FGF2 is widely expressed in the nervous system.

In which tissues of sheep is FGF2 primarily expressed?

FGF2 is mainly expressed in tissues such as mammary glands and ovaries of sheep.

What protein does FGF2 share high homology with?

FGF1 has a high degree of homology with FGF2.

What diseases is FGF2 involved in?

FGF2 is involved in diseases such as cardiovascular disease, breast disease and bone homeostasis.

How does FGF2 regulate bone homeostasis?

FGF2 negatively regulates bone homeostasis.