Recombinant Mouse Fxn Protein, Myc/DDK-tagged

• Cat.No.: Fxn-3112M
• Product Overview: Purified recombinant protein of mouse full-length frataxin (Fxn), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1.
• Molecular Mass: 23.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Fxn frataxin [ Mus musculus (house mouse) ]
• Official Symbol: Fxn
• Synonyms: FXN; frataxin; frataxin, mitochondrial; Friedreich ataxia; FA; X25; FARR; Frda
• Gene ID: 14297
• mRNA Refseq: NM_008044
• Protein Refseq: NP_032070
• UniProt ID: O35943