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Recombinant Mouse Gaa Protein, His-tagged

Cat.No. : Gaa-162M
Product Overview : Recombinant Mouse Gaa(Glu70~Phe245) fused with His tag at N-terminal was expressed in E. coli.
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  • Gene Information
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Description : Gaa played an important role in many functions.
Source : E. coli
Species : Mouse
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 23.5kDa
Identity : Reconstitute in PBS or others
Protein length : Glu70~Phe245
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : Gaa glucosidase, alpha, acid [ Mus musculus ]
Official Symbol : Gaa
Synonyms : GAA; glucosidase, alpha, acid; lysosomal alpha-glucosidase; acid maltase; E430018M07Rik;
Gene ID : 14387
mRNA Refseq : NM_001159324
Protein Refseq : NP_001152796

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does GAA protein relate to other enzymes involved in glycogen metabolism? 11/09/2021

GAA protein is one of several enzymes involved in glycogen metabolism, each playing a specific role in glycogen breakdown.

What are the treatment options for Pompe disease? 02/27/2021

Enzyme replacement therapy (ERT) and gene therapy are two treatment options available for Pompe disease patients to replace or correct the deficient GAA protein.

Are there any other diseases or conditions related to GAA protein deficiency? 09/30/2020

GAA protein deficiency is primarily associated with Pompe disease, but there are other glycogen storage diseases related to deficiencies of different enzymes.

How does ERT work in treating Pompe disease? 05/30/2020

ERT involves the infusion of recombinant GAA protein to replace the missing or deficient enzyme in Pompe disease patients.

Can GAA protein therapy reverse the effects of Pompe disease? 05/03/2016

While GAA protein therapy can improve the symptoms and quality of life for Pompe disease patients, it may not fully reverse the damage caused by the disease.

Customer Reviews (3)

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Reviews
08/11/2020

    Additionally, cost-effectiveness, competitive pricing, and bulk purchase options can also be advantageous for researchers working within limited budgets.

    09/05/2019

      The ability to customize the GAA protein variants or modifications offered by the manufacturer is also advantageous, as it allows me to tailor the protein to my specific research objectives.

      01/28/2018

        I appreciate the manufacturer's commitment to maintaining exceptional protein quality standards, which ensures reliable and consistent results in my trials.

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