Recombinant Mouse Gaa Protein, His-tagged
Cat.No. : | Gaa-162M |
Product Overview : | Recombinant Mouse Gaa(Glu70~Phe245) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Gaa played an important role in many functions. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 23.5kDa |
Identity : | Reconstitute in PBS or others |
Protein length : | Glu70~Phe245 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others |
Gene Name : | Gaa glucosidase, alpha, acid [ Mus musculus ] |
Official Symbol : | Gaa |
Synonyms : | GAA; glucosidase, alpha, acid; lysosomal alpha-glucosidase; acid maltase; E430018M07Rik; |
Gene ID : | 14387 |
mRNA Refseq : | NM_001159324 |
Protein Refseq : | NP_001152796 |
Products Types
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◆ Lysates | ||
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◆ Assay kits | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (5)
Ask a questionGAA protein is one of several enzymes involved in glycogen metabolism, each playing a specific role in glycogen breakdown.
Enzyme replacement therapy (ERT) and gene therapy are two treatment options available for Pompe disease patients to replace or correct the deficient GAA protein.
GAA protein deficiency is primarily associated with Pompe disease, but there are other glycogen storage diseases related to deficiencies of different enzymes.
ERT involves the infusion of recombinant GAA protein to replace the missing or deficient enzyme in Pompe disease patients.
While GAA protein therapy can improve the symptoms and quality of life for Pompe disease patients, it may not fully reverse the damage caused by the disease.
Customer Reviews (3)
Write a reviewAdditionally, cost-effectiveness, competitive pricing, and bulk purchase options can also be advantageous for researchers working within limited budgets.
The ability to customize the GAA protein variants or modifications offered by the manufacturer is also advantageous, as it allows me to tailor the protein to my specific research objectives.
I appreciate the manufacturer's commitment to maintaining exceptional protein quality standards, which ensures reliable and consistent results in my trials.
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