| Cat.No. : |
Gadd45gip1-199M |
| Product Overview : |
Purified recombinant protein of full-length mouse growth arrest and DNA-damage-inducible, gamma interacting protein 1 (Gadd45gip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
| Description : |
Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. |
| Source : |
HEK293T |
| Species : |
Mouse |
| Tag : |
MYC/DDK |
| Molecular Mass : |
26.3 kDa |
| Purity : |
>80%, as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : |
Store at -80 centigrade after receiving vials. |
| Concentration : |
>50 ug/mL as determined by microplate BCA method |
| Storage Buffer : |
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.