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Recombinant Mouse Gfap protein, His & GST-tagged

Cat.No. : Gfap-888M
Product Overview : Recombinant Mouse Gfap aa. (Lys108~Gln211 (Accession # P03995)) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Mouse
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 44.8kDa
Protein length : Lys108~Gln211 (Accession # P03995)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Characteristic : The isoelectric point is 5.6.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Gene Name : Gfap glial fibrillary acidic protein [ Mus musculus (house mouse) ]
Official Symbol : Gfap
Synonyms : Gfap; glial fibrillary acidic protein; AI836096; intermediate filament protein
Gene ID : 14580
mRNA Refseq : NM_001131020.1
Protein Refseq : NP_001124492.1
UniProt ID : P03995

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the main function of GFAP in the central nervous system? 04/04/2022

GFAP is crucial for maintaining the structure and function of astrocytes in the CNS.

How is GFAP used as a biomarker in neurological studies? 03/12/2022

GFAP is used as a biomarker to assess astrocyte activation and neural damage.

How does GFAP contribute to the structure and support of astrocytes? 01/27/2022

It forms intermediate filaments, providing mechanical support and stability to astrocytes.

What role does GFAP play in the response to brain injury? 12/14/2020

It plays a protective role, participating in the glial scar formation post-injury.

How can dysregulation of GFAP affect neural function? 11/28/2020

Dysregulation of GFAP can lead to impaired astrocyte function and neural dysfunction.

In which conditions is an increase in GFAP levels observed? 05/16/2020

Increased GFAP levels are observed in gliosis, neurodegenerative diseases, and brain injuries.

Are there therapeutic interventions targeting GFAP for neurological disorders? 01/28/2020

Therapeutic interventions may aim at modulating GFAP expression to mitigate neural damage.

Customer Reviews (3)

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Reviews
05/11/2022

    Fast, efficient customer service.

    12/12/2021

      Product works great in assays.

      07/16/2021

        No problems, satisfied customer.

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