Recombinant Mouse Gfer Protein, MYC/DDK-tagged
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| Cat.No. : | Gfer-587M |
| Product Overview : | Purified recombinant protein of full-length mouse growth factor, augmenter of liver regeneration (Gfer), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
| Description : | FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. |
| Source : | HEK293T |
| Species : | Mouse |
| Tag : | MYC/DDK |
| Molecular Mass : | 22.9 kDa |
| Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : | Store at -80 centigrade after receiving vials. |
| Concentration : | >50 μg/mL as determined by microplate BCA method |
| Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Gene Name : | Gfer growth factor, augmenter of liver regeneration [ Mus musculus (house mouse) ] |
| Official Symbol : | Gfer |
| Synonyms : | Gfer; growth factor, augmenter of liver regeneration; Alr; ERV1; FAD-linked sulfhydryl oxidase ALR; augmenter of liver regeneration; growth factor, erv1-like (augmenter of liver regeneration); EC 1.8.3.2 |
| Gene ID : | 11692 |
| mRNA Refseq : | NM_023040 |
| Protein Refseq : | NP_075527 |
| UniProt ID : | P56213 |
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◆ Lysates
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