Recombinant Mouse Ggh Protein, Myc/DDK-tagged

• Cat.No.: Ggh-3201M
• Product Overview: Purified recombinant protein of mouse full-length gamma-glutamyl hydrolase (Ggh), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. Acts as endopeptidase. Lysosomal enzyme is activated by sulfhydryl compounds.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 35.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ggh gamma-glutamyl hydrolase [ Mus musculus (house mouse) ]
• Official Symbol: Ggh
• Synonyms: Ggh; gamma-glutamyl hydrolase; gamma-; gamma-GH; gamma-glutamyl hydrolase; FGPH; GH; conjugase; folylpolyglutamate hydrolase; gamma-Glu-x carboxypeptidase; EC 3.4.19.9
• Gene ID: 14590
• mRNA Refseq: NM_010281
• Protein Refseq: NP_034411
• UniProt ID: Q9Z0L8