Recombinant Mouse GRK2 Protein (1-689 aa), His-SUMO-tagged

• Cat.No.: GRK2-1920M
• Product Overview: Recombinant Mouse GRK2 Protein (1-689 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Full Length.

Specification

• Description: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them.
• Source: E. coli
• Species: Mouse
• Tag: His-SUMO
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 95.6 kDa
• Protein length: 1-689 aa
• AA Sequence: MADLEAVLADVSYLMAMEKSKATPA ARASKKILLPEPSIRSVMQKYLEDR GEVTFEKIFSQKLGYLLFRDFCLNH LEEAKPLVEFYEEIKKYEKLETEEE RVVRSREIFDSYIMKELLACSHPFS KNATEHVQGHLVKKQVPPDLFQPYI EEICQNLRGDVFQKFIESDKFTRFC QWKNVELNIHLTMNDFSVHRIIGRG GFGEVYGCRKADTGKMYAMKCLDKK RIKMKQGETLALNERIMLSLVSTGD CPFIVCMSYAFHTPDKLSFILDLMN GGDLHYHLSQHGVFSEADMRFYAAE IILGLEHMHNRFVVYRDLKPANILL DEHGHVRISDLGLACDFSKKRPHAS VGTHGYMAPEVLQKGVAYDSSADWF SLGCMLFKLLRGHSPFRQHKTKDKH EIDRMTLTMAVELPDSFSPELRSLL EGLLQRDVNRRLGCLGRGAQEVKES PFFRSLDWQMVFLQKYPPPLIPPRG EVNAADAFDIGSFDEEDTKGIKLLD SDQELYRNFPLTISERWQQEVAETV FDTINAETDRLEARKKAKNKQLGHE EDYALGKDCIVHGYMSKMGNPFLTQ WQRRYFYLFPNRLEWRGEGEAPQSL LTMEEIQSVEETQIKERKCLLLKIR GGKQFVLQCDSDPELVQWKKELRDA YREAQQLVQRVPKMKNKPRSPVVEL SKVPLIQRGSANGL
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: Grk2 G protein-coupled receptor kinase 2 [ Mus musculus (house mouse) ]
• Official Symbol: GRK2
• Synonyms: Adrbk1; Bark-1; Adrbk-1; beta ARK; betaARK1
• Gene ID: 110355
• mRNA Refseq: NM_001290818
• Protein Refseq: NP_001277747
• UniProt ID: Q99MK8