Recombinant Mouse Gsdme Protein, Myc/DDK-tagged

• Cat.No.: Gsdme-3315M
• Product Overview: Purified recombinant protein of mouse full-length gasdermin E (Gsdme), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Precursor of a pore-forming protein that converts non-inflammatory apoptosis to pyroptosis. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-E, N-terminal) binds to membranes and forms pores, triggering pyroptosis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 56.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Gsdme gasdermin E [ Mus musculus (house mouse) ]
• Official Symbol: Gsdme
• Synonyms: Gsdme; gasdermin E; Dfn; Fin; Dfna; Dfna5; Fin15; Dfna5h; EG14210; 2310037D07Rik; 4932441K13Rik; gasdermin-E; deafness associated tumor suppressor; deafness, autosomal dominant 5 homolog; non-syndromic hearing impairment protein 5 homolog
• Gene ID: 54722
• mRNA Refseq: NM_018769
• Protein Refseq: NP_061239
• UniProt ID: Q9Z2D3