Recombinant Mouse Hck Protein, MYC/DDK-tagged

• Cat.No.: Hck-1100M
• Product Overview: Purified recombinant protein of full-length mouse hemopoietic cell kinase (Hck), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may play a role in the innate immune response and the STAT5 signaling pathway. Alternative translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 59.1 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hck hemopoietic cell kinase [ Mus musculus (house mouse) ]
• Official Symbol: Hck
• Synonyms: Hck; hemopoietic cell kinase; Bmk; AI849071; tyrosine-protein kinase HCK; B cell/myeloid kinase; hematopoietic cell kinase; p56-HCK/p59-HCK; EC 2.7.10.2
• Gene ID: 15162
• mRNA Refseq: NM_010407
• Protein Refseq: NP_034537
• UniProt ID: P08103