Recombinant Mouse Hecw2 Protein, Myc/DDK-tagged

• Cat.No.: Hecw2-3380M
• Product Overview: Purified recombinant protein of mouse full-length HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 (Hecw2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regulation of mitotic metaphase/anaphase transition.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 33.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 [ Mus musculus (house mouse) ]
• Official Symbol: Hecw2
• Synonyms: HECW2; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2; E3 ubiquitin-protein ligase HECW2; NEDD4-related E3 ubiquitin ligase NEDL2; NEDD4-like E3 ubiquitin-protein ligase 2; HECT, C2 and WW domain-containing protein 2; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2, isoform 2; Gm971; Nedl2; mKIAA1301; A730039N16Rik; D030049F17Rik
• Gene ID: 329152
• mRNA Refseq: NM_172655
• Protein Refseq: NP_766243
• UniProt ID: Q6I6G8