Recombinant Mouse Hmgb1 Protein, MYC/DDK-tagged
Cat.No. : | Hmgb1-1134M |
Product Overview : | Purified recombinant protein of full-length mouse high mobility group box 1 (cDNA clone MGC:117897 IMAGE:5036554), complete cds, with C-terminal MYC/DDK tag, was expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 24.9 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 µg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Hmgb1 high mobility group box 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Hmgb1 |
Synonyms : | Hmgb1; high mobility group box 1; p30; Hmg1; HMG-1; SBP-1; high mobility group protein B1; amphoterin; high mobility group protein 1 |
Gene ID : | 15289 |
mRNA Refseq : | NM_010439 |
Protein Refseq : | NP_034569 |
UniProt ID : | P63158 |
Products Types
◆ Recombinant Protein | ||
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HMGB1-2246H | Recombinant Human HMGB1 Protein, His-tagged | +Inquiry |
HMGB1-145H | Active Recombinant Human HMGB1 Protein (Met1-Glu215), C-His tagged, Animal-free, Carrier-free | +Inquiry |
HMGB1-0715H | Recombinant Human HMGB1 Protein (M1-E215), Tag Free | +Inquiry |
Hmgb1-1625M | Recombinant Mouse Hmgb1 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
HMGB1-8447B | Active Native Bovine HMGB1 | +Inquiry |
◆ Lysates | ||
HMGB1-2076HCL | Recombinant Human HMGB1 cell lysate | +Inquiry |
HMGB1-1677MCL | Recombinant Mouse HMGB1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThis protein can promote tumor growth, invasion and angiogenesis, and plays an important role in tumor immune evasion.
Yes, HMGB1 protein plays an important role in tumor metastasis, particularly by promoting invasion of tumor cells and migration of the hematopoietic system.
Is involved in inflammatory response, vascular damage, and thrombosis in cardiovascular disease and may be associated with myocardial ischemia-reperfusion injury.
HMGB1 protein can promote the activation, chemotaxis and inflammatory response of immune cells, and is also involved in regulating the balance of autoimmune response.
HMGB1 protein is associated with processes such as chronic inflammation and insulin resistance in diabetes and may be a potential target for treatment and prevention.
The protein is involved in pathological processes such as liver fibrosis, hepatitis, and liver cancer in liver disease and may be a target for therapeutic strategies.
Customer Reviews (3)
Write a reviewBroad storage conditions of HMGB1ins make the experimental process more stable and reliable, which provides a strong guarantee for scientific research.
I found that tHMGB1 exhibited very good stability during storage, which allowed us to perform experiments easily and obtain reliable results.
The anti-contamination ability of HMGB1 was excellent in Western blot, and the contamination problem in the experiment was avoided.
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