Recombinant Mouse Hpse protein, His-tagged
Cat.No. : | Hpse-704M |
Product Overview : | Recombinant Mouse Hpse aa. (Glu280~Leu412 (Accession # Q6YGZ1)) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an endoglucuronidase enzyme that plays an important role in tumor invasion and metastasis. The encoded preproprotein undergoes proteolytic processing to generate an active heterodimeric enzyme that cleaves the heparan sulfate proteoglycans associated with the cell surface and extracellular matrix. Mice lacking the encoded protein do not show any prominent pathological alterations under normal conditions but fail to develop albuminuria and renal damage in response to drug-induced diabetes. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 16 kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Glu280~Leu412 (Accession # Q6YGZ1) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 6.6. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | Hpse heparanase [ Mus musculus (house mouse) ] |
Official Symbol : | Hpse |
Synonyms : | Hpse; heparanase; Hpa; HSE1; Hpr1; endo-glucoronidase; endoglycosidase heparanase |
Gene ID : | 15442 |
mRNA Refseq : | NM_152803.5 |
Protein Refseq : | NP_690016.1 |
UniProt ID : | Q6YGZ1 |
Products Types
◆ Recombinant Protein | ||
HPSE-5019H | Recombinant Human HPSE Protein, GST-tagged | +Inquiry |
HPSE-2252H | Recombinant Human HPSE Protein, His-tagged | +Inquiry |
HPSE-2251H | Recombinant Human HPSE Protein, His-tagged | +Inquiry |
HPSE-2562R | Recombinant Rat HPSE Protein, His (Fc)-Avi-tagged | +Inquiry |
HPSE-7838M | Active Recombinant Mouse HPSE Protein, His-tagged | +Inquiry |
◆ Lysates | ||
HPSE-5393HCL | Recombinant Human HPSE 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionBy regulating the tumor microenvironment and the function of immune cells, HPSE protein participates in the process of tumor immune evasion.
Yes, the mechanism by which HPSE proteins act in relation to tumor immunotherapy has potential applications in this regard.
The protein plays an important role in liver fibrosis and participates in the regulation of liver tissue fibrosis through mechanisms such as collagen degradation.
HPSE protein is involved in regulating tumor invasion and metastasis by degrading the basement membrane and promoting cytotoxicity.
The protein plays an important role in collagen degradation, tissue repair and regeneration, participates in epithelial-mesenchymal transformation processes, and affects biological processes such as cell migration and remodeling.
HPSE proteins play an important role in the inflammatory response by participating in mechanisms such as extracellular matrix degradation and mediating cytokine production and release.
Customer Reviews (2)
Write a reviewThe stability of HPSE was still very good under different temperature conditions, indicating that it has excellent thermal stability.
Beacuse high efficiency and wide storage conditions of proteins make the experimental process more convenient and greatly improve the efficiency of scientific research.
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