Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Mouse Hsf1 Protein, MYC/DDK-tagged

Cat.No. : Hsf1-1183M
Product Overview : Purified recombinant protein of full-length mouse heat shock factor 1 (Hsf1), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
  • Specification
  • Gene Information
  • Related Products
Description : DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 55.4 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Hsf1 heat shock factor 1 [ Mus musculus (house mouse) ]
Official Symbol : Hsf1
Synonyms : Hsf1; heat shock factor 1; HSTF; HSTF 1; AA960185; Hsf1beta; Hsf1alpha; heat shock factor protein 1
Gene ID : 15499
mRNA Refseq : NM_008296
Protein Refseq : NP_032322
UniProt ID : P38532

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (7)

Ask a question
In which cellular compartments is HSF1 predominantly localized? 10/06/2022

HSF1 is predominantly localized in the cytoplasm of cells, and it undergoes nuclear translocation upon activation.

What role does HSF1 play in the regulation of protein homeostasis and the heat shock response? 07/14/2022

The role of HSF1 includes regulating protein homeostasis and the heat shock response, ensuring cellular proteostasis.

What diseases or conditions are associated with dysregulation or abnormal expression of HSF1? 11/07/2020

Dysregulation or abnormal expression of HSF1 is associated with conditions such as cancer, neurodegenerative disorders, and metabolic diseases.

How does HSF1 influence cellular processes such as apoptosis and senescence? 06/07/2020

HSF1 influences cellular processes such as apoptosis and senescence, playing a role in cell fate decisions under stress conditions.

What is the primary function of heat shock factor 1 (HSF1) in cellular stress responses? 02/21/2018

Heat shock factor 1 (HSF1) primarily functions in cellular stress responses, orchestrating the heat shock response.

Are there therapeutic implications or potential targets related to HSF1 in diseases involving cellular stress? 12/19/2017

There are potential therapeutic implications related to HSF1 in diseases involving cellular stress, making it a target for drug development.

How does HSF1 become activated in response to cellular stress, and what are its target genes? 07/03/2016

HSF1 becomes activated in response to cellular stress, such as heat shock, and it induces the expression of heat shock proteins.

Customer Reviews (3)

Write a review
Reviews
08/30/2021

    The manufacturer's commitment to open science principles resonated with our lab's dedication to transparent research.

    12/17/2018

      We valued the educational webinars and documentation that enhanced our team's proficiency in utilizing the product.

      12/16/2017

        Its association with impactful research publications contributed to its reputation as a valuable scientific tool.

        Ask a Question for All Hsf1 Products

        Required fields are marked with *

        My Review for All Hsf1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends