Recombinant Mouse IL-18
Cat.No. : | IL18-83M |
Product Overview : | Mouse IL-18 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-18 (IL-18) is a cytokine produced by macrophages and other cells that belongs to the IL-1 superfamily. IL-18 works together with IL-12 to induce cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS). After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-gamma (IFN-gamma) or type II interferon that plays an important role in activating the macrophages or other cells. Apart from its physiological role, IL-18 is also able to induce severe inflammatory reactions, which suggests its role in certain inflammatory disorders. The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL-12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. |
Source : | Yeast |
Species : | Mouse |
Form : | Lyophilized |
Molecular Mass : | 18.1 kDa |
AA Sequence : | NFGRLHCTTA VIRNINDQVL FVDKRQPVFE DMTDIDQSAS EPQTRLIIYM YKDSEVRGLA VTLSVKDSKM STLSCKNKII SFEEMDPPEN IDDIQSDLIF FQKRVPGHNK MEFESSLYEG HFLACQKEDD AFKLILKKKD ENGDKSVMFT LTNLHQS (157) |
Applications : | The Mouse IL-18 protein can be used in cell culture, as an IL-18 ELISA Standard, and as a Western Blot Control. |
Storage : | -20 C |
Gene Name : | Il18 interleukin 18 [ Mus musculus ] |
Official Symbol : | IL18 |
Synonyms : | IL18; interleukin 18; interleukin-18; IL-1 gamma; interleukin-1 gamma; IFN-gamma-inducing factor; interferon gamma-inducing factor; interferon-gamma-inducing factor; Igif; Il-18; |
Gene ID : | 16173 |
mRNA Refseq : | NM_008360 |
Protein Refseq : | NP_032386 |
Pathway : | African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Hypertrophy Model, organism-specific biosystem; |
Function : | cytokine activity; |
Products Types
◆ Recombinant Protein | ||
IL18-1169H | Recombinant Human IL18 Protein, His (Fc)-Avi-tagged | +Inquiry |
Il18-1241M | Recombinant Mouse Il18 Protein, MYC/DDK-tagged | +Inquiry |
IL18-2057R | Recombinant Rhesus Macaque IL18 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL18-3681H | Recombinant Human IL18 protein(Met1-Asp193), GST-tagged | +Inquiry |
IL18-2686R | Recombinant Rat IL18 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL18-344HCL | Recombinant Human IL18 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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