| Description : |
This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. |
| Species : |
Mouse |
| Form : |
Lyophilized |
| Protein Length : |
178 |
| AA Sequence : |
MPGSALLCCLLLLTGMRISRGQYSR EDNNCTHFPVGQSHMLLELRTAFSQ VKTFFQTKDQLDNILLTDSLMQDFK GYLGCQALSEMIQFYLVEVMPQAEK HGPEIKEHLNSLGEKLKTLRMRLRR CHRFLPCENKSKAVEQVKSDFNKLQ DQGVYKAMNEFDIFINCIEAYMMIK MKS |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
