Recombinant Mouse Il18 Protein, MYC/DDK-tagged
Cat.No. : | Il18-1241M |
Product Overview : | Purified recombinant protein of full-length mouse interleukin 18 (Il18), with C-terminal MYC/DDK tag, was expressed in HEK293T cells. |
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Description : | Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc&DDK |
Molecular Mass : | 22.6 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 µg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Il18 interleukin 18 [ Mus musculus (house mouse) ] |
Official Symbol : | Il18 |
Synonyms : | Il18; interleukin 18; Igif; Il-18; interleukin-18; IFN-gamma-inducing factor; IL-1 gamma; interferon gamma-inducing factor; interleukin-1 gamma |
Gene ID : | 16173 |
mRNA Refseq : | NM_008360 |
Protein Refseq : | NP_032386 |
UniProt ID : | P70380 |
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◆ Lysates | ||
IL18-344HCL | Recombinant Human IL18 lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewEffective in inflammation models.
High stability in serum.
Suitable for ELISA.
Q&As (10)
Ask a questionCo-immunoprecipitation, co-localization studies, and pathway inhibition assays decipher IL18's interactions with signaling molecules and pathways.
Therapeutic antibody trials, in vitro drug screens, and disease model assessments assess IL18-targeted interventions in autoimmune diseases.
Xenograft models, intravital imaging, and tissue-specific knockout approaches unravel IL18's kinetics and effects within complex in vivo environments.
Flow cytometry, chemotaxis assays, and functional cell assays examine IL18's impact on immune cell activation, migration, and effector functions.
Surface plasmon resonance, mutational studies, and phosphoproteomics illuminate IL18's receptor interactions and downstream signal transduction pathways.
Immunophenotyping, cytokine profiling, and gene expression analyses elucidate IL18's influence on Th cell polarization and immune balance.
ChIP assays, promoter analyses, and epigenetic profiling uncover the regulatory mechanisms underlying IL18 gene expression dynamics.
Disease models, knockout mice, and co-stimulation studies explore IL18's involvement in inflammatory conditions and its interplay with other proinflammatory mediators.
Tumor models, immune profiling, and immunotherapeutic studies investigate IL18's modulation of the tumor microenvironment and its implications for cancer therapy.
Caspase assays, cytokine ELISAs, and microscopy techniques unveil the activation of inflammasomes and IL18's contribution to pyroptosis and cytokine storms.
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