Active Recombinant Mouse Il1r2 protein(Met1-Glu355), hFc-tagged
Cat.No. : | Il1r2-8699M |
Product Overview : | Recombinant Mouse IL1R2 (P27931) (Met1-Glu355) was expressed in HEK293, fused with the Fc region of Human IgG1 at the C-terminus. |
- Specification
- Gene Information
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Source : | HEK293 |
Species : | Mouse |
Tag : | C-hFc |
Protein length : | Met1-Glu355 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its ability to bind biotinylated recombinant human IL1α in a functional ELISA. |
Molecular Mass : | The recombinant mouse IL1R2 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 583 amino acids and has a predicted molecular mass of 65.1 kDa. The apparent molecular mass of the protein is approximately 91 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 85 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Il1r2 interleukin 1 receptor, type II [ Mus musculus ] |
Official Symbol : | Il1r2 |
Synonyms : | IL1R2; interleukin 1 receptor, type II; interleukin-1 receptor type 2; IL-1R-2; IL-1RT2; IL-1RT-2; IL-1R-beta; IL-1 type II receptor; IL-1 receptor beta chain; interleukin-1 receptor beta; interleukin-1 receptor type II; CD121 antigen-like family member B; CD121b; Il1r-2; |
Gene ID : | 16178 |
mRNA Refseq : | NM_010555 |
Protein Refseq : | NP_034685 |
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◆ Lysates | ||
IL1R2-1376MCL | Recombinant Mouse IL1R2 cell lysate | +Inquiry |
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IL1R2-1108HCL | Recombinant Human IL1R2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThe intracellular domain of IL1R2 has functional significance; engineered constructs clarify its role.
Glycosylation of IL1R2 affects its IL-1 ligand interaction, and glycoproteomics methods can reveal critical glycosylation sites.
Engineered IL1R2 variants offer insights into its mechanisms and therapeutic potential.
IL1R2's presence impacts IL-1 ligand signaling through competition with IL1R1; genetic manipulations unveil this interaction.
Post-translational modifications, including ubiquitination, influence IL1R2's stability.
IL1R2 expression responds to inflammation; transcription factors play a role in its regulation.
Super-resolution microscopy helps understand IL1R2's trafficking and subcellular dynamics in detail.
Specific structural elements of IL1R2 contribute to its decoy role; X-ray crystallography provides insights into ligand binding.
Ectodomain shedding contributes to IL1R2's soluble decoy role; specific enzymes are involved.
IL1R2's interaction with accessory proteins is significant for its decoy function.
Customer Reviews (3)
Write a reviewHigh specificity.
Good for flow cytometry.
Suitable for co-immunoprecipitation.
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