| Description : |
Predicted to enable cytokine receptor activity. Involved in positive regulation of chemokine production; positive regulation of cold-induced thermogenesis; and positive regulation of macrophage activation. Acts upstream of or within several processes, including defense response to protozoan; negative regulation of T-helper 1 cell differentiation; and positive regulation of immune effector process. Predicted to be located in several cellular components, including centriolar satellite; extracellular space; and nucleoplasm. Predicted to be part of receptor complex. Is expressed in several structures, including adrenal medulla; early conceptus; hemolymphoid system; medulla oblongata basal plate mantle layer; and reproductive system. Used to study asthma. Human ortholog(s) of this gene implicated in several diseases, including acne; allergic conjunctivitis; autoimmune disease (multiple); human immunodeficiency virus infectious disease; and renal tuberculosis. Orthologous to human IL4R (interleukin 4 receptor). |
| Source : |
HEK293 |
| Species : |
Mouse |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
26.3 kDa |
| Protein Length : |
810 |
| AA Sequence : |
MGRLCTKFLTSVGCLILLLVTGSGS IKVLGEPTCFSDYIRTSTCEWFLDS AVDCSSQLCLHYRLMFFEFSENLTC IPRNSASTVCVCHMEMNRPVQSDRY QMELWAEHRQLWQGSFSPSGNVKPL APDNLTLHTNVSDEWLLTWNNLYPS NNLLYKDLISMVNISREDNPAEFIV YNVTYKEPRLSFPINILMSGVYYTA RVRVRSQILTGTWSEWSPSITWYNH FQLPLIQRLPLGVTISCLCIPLFCL FCYFSITKIKKIWWDQIPTPARSPL VAIIIQDAQVPLWDKQTRSQESTKY PHWKTCLDKLLPCLLKHRVKKKTDF PKAAPTKSLQSPGKAGWCPMEVSRT VLWPENVSVSVVRCMELFEAPVQNV EEEEDEIVKEDLSMSPENSGGCGFQ ESQADIMARLTENLFSDLLEAENGG LGQSALAESCSPLPSGSGQASVSWA CLPMGPSEEATCQVTEQPSHPGPLS GSPAQSAPTLACTQVPLVLADNPAY RSFSDCCSPAPNPGELAPEQQQADH LEEEEPPSPADPHSSGPPMQPVESW EQILHMSVLQHGAAAGSTPAPAGGY QEFVQAVKQGAAQDPGVPGVRPSGD PGYKAFSSLLSSNGIRGDTAAAGTD DGHGGYKPFQNPVPNQSPSSVPLFT FGLDTELSPSPLNSDPPKSPPECLG LELGLKGGDWVKAPPPADQVPKPFG DDLGFGIVYSSLTCHLCGHLKQHHS QEEGGQSPIVASPGCGCCYDDRSPS LGSLSGALESCPEGIPPEANLMSAP KTPSNLSGEGKGPGHSPVPSQTTEV PVGALGIAVS |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
