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Recombinant Mouse Il6ra Protein, MYC/DDK-tagged

Cat.No. : Il6ra-1246M
Product Overview : Purified recombinant protein of full-length mouse interleukin 6 receptor, alpha (Il6ra), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
  • Specification
  • Gene Information
  • Related Products
Description : Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 50.9 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Il6ra interleukin 6 receptor, alpha [ Mus musculus (house mouse) ]
Official Symbol : Il6ra
Synonyms : Il6ra; interleukin 6 receptor, alpha; Il6r; CD126; IL-6R; IL-6RA; IL-6R-alpha; interleukin-6 receptor subunit alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL-6R 1; IL-6R subunit alpha
Gene ID : 16194
mRNA Refseq : NM_010559
Protein Refseq : NP_034689
UniProt ID : P22272

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the pharmacological action of Il6ra? 07/10/2021

Il6ra blocks the binding of the interleukin-6 receptor by acting on it, thereby affecting its immunomodulatory effect and reducing inflammation.

Which diseases is Il6ra recombinant more effective in treating? 06/21/2021

The efficacy of Il6ra is related to the severity of the disease, disease type and individual differences of patients, and should be judged by professional physicians according to the situation.

What diseases can recombinant Il6ra be used to treat? 02/10/2020

Il6ra can be used to treat rheumatoid arthritis, psoriasis, alopecia areata and other autoimmune diseases.

Does Il6ra treat diseases with side effects? 08/14/2019

Almost all treatments have some kind of side effect, but the occurrence of side effects can be reduced with proper dosing and monitoring.

What is the mechanism of Il6ra? 08/08/2019

Recombinant Il6ra inhibits the immune response by inhibiting the cytokine activity of interleukin-6.

What are the clinical prospects of Il6ra? 03/25/2019

In addition to the autoimmune diseases mentioned above, Il6ra may also be used in the future to treat chronic inflammatory bowel disease, neurodegenerative diseases, and cancer.

Customer Reviews (3)

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Reviews
12/08/2021

    It has good effect and stability in gene expression regulation.

    05/31/2020

      Will not interact with other drugs, will not affect.

      04/12/2019

        The application performance is stable in common colorimetric reactions.

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