Recombinant Mouse Il6ra Protein, MYC/DDK-tagged
Cat.No. : | Il6ra-1246M |
Product Overview : | Purified recombinant protein of full-length mouse interleukin 6 receptor, alpha (Il6ra), with C-terminal MYC/DDK tag, was expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 50.9 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 µg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Il6ra interleukin 6 receptor, alpha [ Mus musculus (house mouse) ] |
Official Symbol : | Il6ra |
Synonyms : | Il6ra; interleukin 6 receptor, alpha; Il6r; CD126; IL-6R; IL-6RA; IL-6R-alpha; interleukin-6 receptor subunit alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL-6R 1; IL-6R subunit alpha |
Gene ID : | 16194 |
mRNA Refseq : | NM_010559 |
Protein Refseq : | NP_034689 |
UniProt ID : | P22272 |
Products Types
◆ Recombinant Protein | ||
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IL6RA-3322H | Active Recombinant Human IL6RA protein | +Inquiry |
Il6ra-583M | Recombinant Mouse Il6ra protein, His-tagged | +Inquiry |
Il6ra-001M | Active Recombinant Mouse IL6RA, MIgG2a Fc-tagged | +Inquiry |
◆ Lysates | ||
IL6R-2590MCL | Recombinant Mouse IL6R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (6)
Ask a questionIl6ra blocks the binding of the interleukin-6 receptor by acting on it, thereby affecting its immunomodulatory effect and reducing inflammation.
The efficacy of Il6ra is related to the severity of the disease, disease type and individual differences of patients, and should be judged by professional physicians according to the situation.
Il6ra can be used to treat rheumatoid arthritis, psoriasis, alopecia areata and other autoimmune diseases.
Almost all treatments have some kind of side effect, but the occurrence of side effects can be reduced with proper dosing and monitoring.
Recombinant Il6ra inhibits the immune response by inhibiting the cytokine activity of interleukin-6.
In addition to the autoimmune diseases mentioned above, Il6ra may also be used in the future to treat chronic inflammatory bowel disease, neurodegenerative diseases, and cancer.
Customer Reviews (3)
Write a reviewIt has good effect and stability in gene expression regulation.
Will not interact with other drugs, will not affect.
The application performance is stable in common colorimetric reactions.
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