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Recombinant Mouse Interleukin 1 Receptor Antagonist, His-tagged

Cat.No. : Il1rn-5593M
Product Overview : Recombinant mouse Il1rnprotein, fused to His-tag at N-terminus was expressed in E. coli and purifiedby using conventional chromatography techniques.
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  • Gene Information
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Cat. No. : Il1rn-5593M
Description : Interleukin1 receptor antagonist (Il1rn), alsoknown as IL1-RA, is a member of the interleukin 1 cytokine family. IL1RN mayrepresent a reservoir of IL-1 inhibitors, released upon cell death, whosefunction is no limit the pro-inflammatory signals but most prominently bymononuclear phagocytes and keratinocytes. IL1RN is reported to be associatedwith increased risk of osteoporotic fractures and gastric cancer.
Form : Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol.
Molecular Weight : 20.0 kDa(177aa), confirmed by MALDI-TOF.
Purity : > 95%by SDS-PAGE
Concentration : 1 mg/ml(determined by Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MGSHMRPSGK RPCKMQAFRI WDTNQKTFYL RNNQLIAGYL QGPNIKLEEKIDMVPIDLHS VFLGIHGGKL CLSCAKSGDD IKLQLEEVNI TDLSKNKEEDKRFTFIRSEK GPTTSFESAA CPGWFLCTTL EADRPVSLTN TPEEPLIVTK FYFQEDQ
Storage : Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : Il1rn interleukin 1 receptorantagonist [ Mus musculus ]
Official Symbol : Il1rn
Synonyms : Il1rn; interleukin 1 receptor antagonist;ICIL-1RA; IL1F3; IL1RA; MGC10430; DIRA; MVCD4; IL-1ra3; IL1RN (IL1F3);IL-1ra; F630041P17Rik; interleukin-1 receptor antagonist protein; IRAP;IL-1RN; IL1 inhibitor; intracellular IL-1 receptor antagonist type II;intracellular interleukin-1 receptor antagonist (icIL-1ra); type IIinterleukin-1 receptor antagonist; Anakinra; OTTHUMP00000162022;OTTHUMP00000162023; OTTHUMP00000162024; OTTHUMP00000203731
Gene ID : 16181
mRNA Refseq : NM_001039701
Protein Refseq : NP_001034790
UniProt ID : P25085
Chromosome Location : 2 A3; 2 10.0 cM
Pathway : IL-1 Signaling Pathway
Function : interleukin-1 Type I receptor antagonistactivity; interleukin-1 Type II receptor antagonist activity; interleukin-1receptor antagonist activity; interleukin-1 receptor binding; interleukin-1,Type I receptor binding; interleukin-1, Type II receptor binding; receptoractivity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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