Species : |
Mouse |
Source : |
Sf21 Cells |
Tag : |
Non |
Description : |
Interleukin 1 receptor type II (IL1R2), also known as CD121b (Cluster of Differentiation 121b), is a transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and endothelial cells. It is a decoy receptor known for its ability to buffer IL-1 effects. IL-1RII is involved in the control of the proinflammatory state that takes place in the endometrium during the premenstrual and menstrual periods. IL-1RII can neutralize IL-1 beta and counteract its effect on endometrial stromal cells, and may provide a new clinical strategy for the treatment of endometriosis. |
Molecular Weight : |
The predicted molecular weight of Recombinant Mouse IL-1 RII is Mr 64.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-80 kDa. |
State Of Matter : |
Lyophilized. |
Purity : |
>95% by SDS Page and analyzed by silver stain. |
Endotoxin : |
<1.0 EU/µg as determined by the LAL method. |
Storage And Stability : |
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |