Recombinant Mouse IRAK4 Protein, His (Fc)-Avi-tagged

Cat.No. : IRAK4-4597M
Product Overview : Recombinant Mouse IRAK4 with His (Fc)-Avi tag was expressed and purified
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Source : HEK293
Species : Mouse
Tag : His (Fc)-Avi
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : ≥85% by SDS-PAGE
Stability : Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Storage Buffer : PBS buffer
Gene Name : Irak4 interleukin-1 receptor-associated kinase 4 [ Mus musculus ]
Official Symbol : IRAK4
Gene ID : 266632
mRNA Refseq : NM_029926.5
Protein Refseq : NP_084202.2
UniProt ID : Q8R4K2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What conditions are associated with IRAK4 dysregulation? 11/04/2020

Rheumatoid arthritis, lupus, inflammatory bowel diseases, and certain cancers may involve IRAK4.

Are there any ongoing clinical trials involving IRAK4 inhibitors? 10/07/2020

Yes, several trials are investigating IRAK4 inhibitors' effectiveness and safety in various diseases.

What are the methods used to target IRAK4 in treatment? 11/25/2017

Small molecule inhibitors and monoclonal antibodies are primary methods for modulating IRAK4 activity.

How does the expression of IRAK4 differ in healthy individuals and those with autoimmune diseases? 11/01/2016

Individuals with autoimmune diseases often show increased IRAK4 expression compared to healthy individuals.

How does IRAK4 inhibition impact the immune response? 01/17/2016

By blocking IRAK4, the overactive immune response in certain diseases can be suppressed.

Customer Reviews (3)

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11/16/2021

    Its potency and specificity make it a valuable tool for studying specific biological pathways or mechanisms.

    03/01/2020

      Their technical expertise and experience in the field allow them to provide invaluable guidance and assistance.

      07/16/2018

        They can offer insights on experimental design, optimal usage protocols, and troubleshoot any challenges that may arise during the course of the trial.

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