Recombinant Mouse Irak4 protein(Ser169-Ala459), His-tagged

Cat.No. : Irak4-0058M
Product Overview : Recombinant Mouse Irak4 protein(Ser169-Ala459)(Q8R4K2), fused with N-terminal His tag, was expressed in E.coli.
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Source : E.coli
Species : Mouse
Tag : N-His
Protein length : Ser169-Ala459
Form : Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Molecular Mass : 34.44 kDa
Purity : >90% as determined by SDS-PAGE.
Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt.
Reconstitution : Reconstitute in sterile water for a stock solution.
Gene Name : Irak4 interleukin-1 receptor-associated kinase 4 [ Mus musculus ]
Official Symbol : Irak4
Synonyms : Irak4
Gene ID : 266632
mRNA Refseq : NM_029926
Protein Refseq : NP_084202
UniProt ID : Q8R4K2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What conditions are associated with IRAK4 dysregulation? 11/04/2020

Rheumatoid arthritis, lupus, inflammatory bowel diseases, and certain cancers may involve IRAK4.

Are there any ongoing clinical trials involving IRAK4 inhibitors? 10/07/2020

Yes, several trials are investigating IRAK4 inhibitors' effectiveness and safety in various diseases.

What are the methods used to target IRAK4 in treatment? 11/25/2017

Small molecule inhibitors and monoclonal antibodies are primary methods for modulating IRAK4 activity.

How does the expression of IRAK4 differ in healthy individuals and those with autoimmune diseases? 11/01/2016

Individuals with autoimmune diseases often show increased IRAK4 expression compared to healthy individuals.

How does IRAK4 inhibition impact the immune response? 01/17/2016

By blocking IRAK4, the overactive immune response in certain diseases can be suppressed.

Customer Reviews (3)

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11/16/2021

    Its potency and specificity make it a valuable tool for studying specific biological pathways or mechanisms.

    03/01/2020

      Their technical expertise and experience in the field allow them to provide invaluable guidance and assistance.

      07/16/2018

        They can offer insights on experimental design, optimal usage protocols, and troubleshoot any challenges that may arise during the course of the trial.

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