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Recombinant Mouse Irf4 Protein, Myc/DDK-tagged

Cat.No. : Irf4-3575M
Product Overview : Purified recombinant protein of mouse full-length interferon regulatory factor 4 (Irf4), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 52 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Irf4 interferon regulatory factor 4 [ Mus musculus (house mouse) ]
Official Symbol : Irf4
Synonyms : IRF4; interferon regulatory factor 4; NF-EM5; PU.1 interaction partner; transcriptional activator PIP; Sfpi1/PU.1 interaction partner; lymphocyte-specific interferon regulatory factor; Spip; IRF-4; LSIRF; AI385587
Gene ID : 16364
mRNA Refseq : NM_013674
Protein Refseq : NP_038702
UniProt ID : Q64287

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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