Active Recombinant Mouse Itga4/Itgb7 protein

• Cat.No.: Itga4/Itgb7-357M
• Product Overview: Recombinant Mouse Itga4(Tyr34-Gln970)/Itgb7(Glu20-Arg724) was expressed in CHO.

Specification

• Source: CHO
• Species: Mouse
• Predicted N Terminal: Tyr34 (Integrin alpha 4), Glu20 (Integrin beta 7)
• Form: Lyophilized from a 0.2 μm filtered solution in PBS.
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with VCAM-1. The ED50 for this effect is typically 0.6-3.6 ug/mL.
• Molecular Mass: Predicted Molecular Mass: 113 (Integrin alpha 4), 84 (Integrin beta 7) kDa;SDS-PAGE: 115 - 170 kDa, reducing conditions.
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity: >95%, by SDS-PAGE with silver staining.
• Stability: Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 200 ug/mL in PBS.

Gene Information

• Gene Name: Itga4 integrin alpha 4 [ Mus musculus ]
• Official Symbol: Itga4
• Synonyms: ITGA4; integrin alpha 4; integrin alpha-4; integrin alpha-IV; LPAM subunit alpha; VLA-4 subunit alpha; VLA-4 receptor, alpha 4 subunit; CD49 antigen-like family member D; lymphocyte Peyer patch adhesion molecules subunit alpha; CD49D
• Gene ID: 16401
• mRNA Refseq: NM_010576
• Protein Refseq: NP_034706
• UniProt ID: Q00651
• Chromosome Location: 2 C3; 2 47.38 Cm
• Pathway: Adaptive Immune System, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem
• Function: fibronectin binding; receptor activity