Recombinant Mouse ITGAL Protein (153-325 aa), His-tagged

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Recombinant Mouse ITGAL Protein (153-325 aa), His-tagged

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Cat.No. : ITGAL-589M
Product Overview : Recombinant Mouse ITGAL Protein (153-325 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial.
Description : Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Mice expressing a null mutation of the alpha-L subunit gene donstrate impaired tumor rejection and impaired leukocytes recruitment.
Source : E. coli
Species : Mouse
Tag : His
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 23.7 kDa
Protein length : 153-325 aa
AA Sequence : DLVFLFDGSQ SLDRKDFEKI LEFMKDVMRK LSNTSYQFAA VQFSTDCRTE FTFLDYVKQN KNPDVLLGSV QPMFLLTNTF RAINYVVAHV FKEESGARPD ATKVLVIITD GEASDKGNIS AAHDITRYII GIGKHFVSVQ KQKTLHIFAS EPVEEFVKIL DTFEKLKDLF TDL
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : Itgal integrin alpha L [ Mus musculus ]
Official Symbol : ITGAL
Synonyms : ITGAL; Cd11a; LFA-1; Ly-15; Ly-21; (p180); LFA-1A;
Gene ID : 16408
mRNA Refseq : NM_001253872
Protein Refseq : NP_001240801
UniProt ID : P24063

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