Recombinant Mouse Lmnb2 Protein, MYC/DDK-tagged Lmnb2-1326M

Recombinant Mouse Lmnb2 Protein, MYC/DDK-tagged

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Recombinant Mouse Lmnb2 Protein, MYC/DDK-tagged

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Cat.No. : Lmnb2-1326M
Product Overview : Purified recombinant protein of full-length mouse lamin B2 (Lmnb2), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
Description : This gene encodes a protein component of the nuclear lamina, which provides a structural framework for the nuclear envelope. Defects in this gene were found to cause abnormalities in the shape of neurons. This locus represents one of two B-type lamin genes that may be partially, but not entirely, functionally redundant in neuronal development. Loss of both B-type lamin genes in keratinocytes results in ichthyosis and a skin barrier defect leading to dehydration. Alternative transcriptional initiation and splicing results in multiple transcript variants and protein isoforms, including an isoform with a shorter N-terminal rod domain that may function in nuclear envelope remodeling during spermatogenesis. A related pseudogene is found on chromosome 5.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 67.3 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Lmnb2 lamin B2 [ Mus musculus (house mouse) ]
Official Symbol : Lmnb2
Synonyms : Lmnb2; lamin B2; lamin-B2; lamin B3
Gene ID : 16907
mRNA Refseq : NM_010722
Protein Refseq : NP_034852
UniProt ID : P21619

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