Recombinant Mouse Lmnb2 Protein, MYC/DDK-tagged


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Recombinant Mouse Lmnb2 Protein, MYC/DDK-tagged

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Cat.No. : Lmnb2-1326M
Product Overview : Purified recombinant protein of full-length mouse lamin B2 (Lmnb2), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
Description : This gene encodes a protein component of the nuclear lamina, which provides a structural framework for the nuclear envelope. Defects in this gene were found to cause abnormalities in the shape of neurons. This locus represents one of two B-type lamin genes that may be partially, but not entirely, functionally redundant in neuronal development. Loss of both B-type lamin genes in keratinocytes results in ichthyosis and a skin barrier defect leading to dehydration. Alternative transcriptional initiation and splicing results in multiple transcript variants and protein isoforms, including an isoform with a shorter N-terminal rod domain that may function in nuclear envelope remodeling during spermatogenesis. A related pseudogene is found on chromosome 5.
Source : HEK293T
Species : Mouse
Molecular Mass : 67.3 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Lmnb2 lamin B2 [ Mus musculus (house mouse) ]
Official Symbol : Lmnb2
Synonyms : Lmnb2; lamin B2; lamin-B2; lamin B3
Gene ID : 16907
mRNA Refseq : NM_010722
Protein Refseq : NP_034852
UniProt ID : P21619
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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