Recombinant Mouse Lrwd1 Protein, Myc/DDK-tagged
Cat.No. : | Lrwd1-3849M |
Product Overview : | Purified recombinant protein of mouse full-length leucine-rich repeats and WD repeat domain containing 1 (Lrwd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 71.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Lrwd1 leucine-rich repeats and WD repeat domain containing 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Lrwd1 |
Synonyms : | LRWD1; leucine-rich repeats and WD repeat domain containing 1; leucine-rich repeat and WD repeat-containing protein 1; ORC-associated protein; origin recognition complex-associated protein; Orca; AU042569; AW548074; 1200011O22Rik |
Gene ID : | 71735 |
mRNA Refseq : | NM_027891 |
Protein Refseq : | NP_082167 |
UniProt ID : | Q8BUI3 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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