Recombinant Mouse Magi2 Protein, Myc/DDK-tagged

• Cat.No.: Magi2-3905M
• Product Overview: Purified recombinant protein of mouse full-length membrane associated guanylate kinase, WW and PDZ domain containing 2 (Magi2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 141.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 [ Mus musculus (house mouse) ]
• Official Symbol: Magi2
• Synonyms: MAGI2; membrane associated guanylate kinase, WW and PDZ domain containing 2; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; atrophin-1-interacting protein 1; activin receptor interacting protein 1; activin receptor-interacting protein 1; membrane-associated guanylate kinase inverted 2; AIP-1; Acvri1; Magi-2; S-SCAM; Acvrip1; Acvrinp1; mKIAA0705
• Gene ID: 50791
• mRNA Refseq: NM_001170746
• Protein Refseq: NP_001164217
• UniProt ID: Q9WVQ1