Recombinant Mouse Malt1 Protein, Myc/DDK-tagged

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Recombinant Mouse Malt1 Protein, Myc/DDK-tagged

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Cat.No. : Malt1-3911M
Product Overview : Purified recombinant protein of Mouse mucosa associated lymphoid tissue lymphoma translocation gene 1 (Malt1), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. Involved in the induction of T helper 17 cells (Th17) differentiation. Cleaves RC3H1 and ZC3H12A in response to T-cell receptor (TCR) stimulation which releases their cooperatively repressed targets to promote Th17 cell differentiation.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 92.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
SDS-PAGE :

Gene Name : Malt1 MALT1 paracaspase [ Mus musculus (house mouse) ]
Official Symbol : Malt1
Synonyms : MALT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; paracaspase; A630046N12; D430033E09Rik; MGC124469; MGC124470
Gene ID : 240354
mRNA Refseq : NM_172833
Protein Refseq : NP_766421
UniProt ID : Q2TBA3

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