Recombinant Mouse Map2k3 Protein, Myc/DDK-tagged

• Cat.No.: Map2k3-3922M
• Product Overview: Purified recombinant protein of mouse full-length mitogen activated protein kinase kinase 3 (cDNA clone MGC:5915 IMAGE:3497714), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 19.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Map2k3 mitogen-activated protein kinase kinase 3 [ Mus musculus (house mouse) ]
• Official Symbol: Map2k3
• Synonyms: Map2k3; mitogen-activated protein kinase kinase 3; MEK3; MKK3; Prkm; MKK3b; Prkmk3; MAPKK 3; AW212142; dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPK/ERK kinase 3; EC 2.7.12.2
• Gene ID: 26397
• mRNA Refseq: NM_008928
• Protein Refseq: NP_032954
• UniProt ID: O09110