Recombinant Mouse Map3k20 Protein, Myc/DDK-tagged

• Cat.No.: Map3k20-3930M
• Product Overview: Purified recombinant protein of mouse full-length mitogen-activated protein kinase kinase kinase 20 (Map3k20), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Involved in limb development.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 91.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Map3k20 mitogen-activated protein kinase kinase kinase 20 [ Mus musculus (house mouse) ]
• Official Symbol: Map3k20
• Synonyms: Map3k20; mitogen-activated protein kinase kinase kinase 20; Za; Zak; MLTK; HCCS-4; MLTKbe; AV006891; MLTKbeta; MLTKalpha; B230120H23Rik; mitogen-activated protein kinase kinase kinase 20; MLK-like mitogen-activated protein triple kinase; MLK-related kinase; MRK; human cervical cancer suppressor gene 4 protein; leucine zipper- and sterile alpha motif kinase ZAK; leucine zipper- and sterile alpha motif-containing kinase; mitogen-activated protein kinase kinase kinase MLT; mixed lineage kinase-related kinase; sterile alpha motif and leucine zipper containing kinase AZK; EC 2.7.11.25
• Gene ID: 65964
• mRNA Refseq: NM_023057
• Protein Refseq: NP_075544
• UniProt ID: Q9ESL4