Recombinant Mouse Mlkl protein, His-tagged
Cat.No. : | MLKL-9880M |
Product Overview : | Recombinant Mouse Mlkl(1-472aa) fused with His tag was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. |
Source : | HEK293 |
Species : | Mouse |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 56.3kD |
Protein length : | 1-472aa |
AA Sequence : | MDKLGQIIKLGQLIYEQCEKMKYCR KQCQRLGNRVHGLLQPLQRLQAQGK KNLPDDITAALGRFDEVLKEANQQI EKFSKKSHIWKFVSVGNDKILFHEV NEKLRDVWEELLLLLQVYHWNTVSD VSQPASWQQEDRQDAEEDGNENMKV ILMQLQISVEEINKTLKQCSLKPTQ EIPQDLQIKEIPKEHLGPPWTKLKT SKMSTIYRGEYHRSPVTIKVFNNPQ AESVGIVRFTFNDEIKTMKKFDSPN ILRIFGICIDQTVKPPEFSIVMEYC ELGTLRELLDREKDLTMSVRSLLVL RAARGLYRLHHSETLHRNISSSSFL VAGGYQVKLAGFELSKTQNSISRTA KSTKAERSSSTIYVSPERLKNPFCL YDIKAEIYSFGIVLWEIATGKIPFE GCDSKKIRELVAEDKKQEPVGQDCP ELLREIINECRAHEPSQRPSVDGRS LSGRERILERLSAVEESTDKKV |
Purity : | >90% ( SDS-PAGE ) |
Storage : | Store at -20 centigrade for extended storage conserve at -20 centigrade or -80 centigrade. Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Gene Name : | Mlkl mixed lineage kinase domain-like [ Mus musculus ] |
Official Symbol : | Mlkl |
Synonyms : | MLKL; mixed lineage kinase domain-like; mixed lineage kinase domain-like protein; 9130019I15Rik; |
Gene ID : | 74568 |
mRNA Refseq : | NM_029005 |
Protein Refseq : | NP_083281 |
UniProt ID : | Q9D2Y4 |
Chromosome Location : | 8; 8 D3 |
Function : | ATP binding; protein kinase activity; transferase activity, transferring phosphorus-containing groups; |
Products Types
◆ Recombinant Protein | ||
MLKL-1701H | Recombinant Human MLKL Protein (1-471 aa), His-tagged | +Inquiry |
MLKL-0926H | Recombinant Human MLKL Protein (E2-K471), His/GST tagged | +Inquiry |
MLKL-0925H | Recombinant Human MLKL Protein (E2-K471), Tag Free | +Inquiry |
MLKL-1706M | Recombinant Mouse MLKL Protein (1-472 aa), His-tagged | +Inquiry |
MLKL-1098H | Recombinant Human MLKL Protein (1-471 aa), His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
MLKL-1115HCL | Recombinant Human MLKL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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