Recombinant Mouse Nr1i2 protein, His & GST-tagged
Cat.No. : | Nr1i2-1085M |
Product Overview : | Recombinant Mouse Nr1i2 aa. (Tyr205-Gly390 (Accession # O54915) fused with N-terminal His & GST tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Mouse |
Tag : | His & GST |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 48.7kDa. |
Protein length : | Tyr205-Gly390 (Accession # O54915) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 6.6. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | Nr1i2 nuclear receptor subfamily 1, group I, member 2 [ Mus musculus (house mouse) ] |
Official Symbol : | Nr1i2 |
Synonyms : | Nr1i2; nuclear receptor subfamily 1, group I, member 2; PXR; SXR; PXR1; mPXR; PXR.1; PXR.2; nuclear receptor subfamily 1 group I member 2; Pregnane X receptor; orphan nuclear receptor PXR |
Gene ID : | 18171 |
mRNA Refseq : | NM_001098404.1 |
Protein Refseq : | NP_001091874.1 |
UniProt ID : | O54915 |
Products Types
◆ Recombinant Protein | ||
NR1I2-6073H | Recombinant Human NR1I2 Protein, GST-tagged | +Inquiry |
Nr1i2-4487M | Recombinant Mouse Nr1i2 Protein, Myc/DDK-tagged | +Inquiry |
NR1I2-1537H | Recombinant Human NR1I2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NR1I2-0773H | Recombinant Human NR1I2 Protein (S130-S434), Tag Free | +Inquiry |
NR1I2-1300H | Recombinant Human NR1I2 Protein, His-SUMO/MYC-tagged | +Inquiry |
◆ Lysates | ||
NR1I2-3718HCL | Recombinant Human NR1I2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionDysregulation of NR1I2 has been implicated in certain liver diseases and metabolic disorders, where impaired drug metabolism may contribute to disease progression.
NR1I2 can influence the metabolism of chemotherapy drugs, affecting their bioavailability and efficacy in cancer treatment.
Some drugs are designed to modulate NR1I2 activity for therapeutic purposes, aiming to enhance or inhibit its function based on the clinical context.
NR1I2 is activated in response to xenobiotic exposure, leading to the upregulation of enzymes involved in detoxification and elimination of foreign substances.
Yes, genetic variations in NR1I2 can lead to inter-individual differences in drug metabolism, potentially impacting drug efficacy and safety.
Customer Reviews (3)
Write a reviewTheir experienced team is dedicated to resolving any issues or challenges I may encounter during my experiments, providing prompt and effective solutions.
The NR1I2 protein is renowned for its exceptional quality, making it a perfect match for my experimental requirements.
In addition to its high-quality attributes, the manufacturer of the NR1I2 protein offers exemplary technical support.
Ask a Question for All Nr1i2 Products
Required fields are marked with *
My Review for All Nr1i2 Products
Required fields are marked with *
Inquiry Basket