Recombinant Mouse Pi4k2a Protein, Myc/DDK-tagged

• Cat.No.: Pi4k2a-4848M
• Product Overview: Purified recombinant protein of mouse full-length phosphatidylinositol 4-kinase type 2 alpha (cDNA clone MGC:37783 IMAGE:5097465), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Membrane-bound phosphatidylinositol-4 kinase (PI4-kinase) that catalyzes the phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P), a lipid that plays important roles in endocytosis, Golgi function, protein sorting and membrane trafficking and is required for prolonged survival of neurons. Besides, phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P) is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3).
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 71.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pi4k2a phosphatidylinositol 4-kinase type 2 alpha [ Mus musculus (house mouse) ]
• Official Symbol: Pi4k2a
• Synonyms: Pi4k2a; phosphatidylinositol 4-kinase type 2 alpha; Pi4k2; phosphatidylinositol 4-kinase type 2-alpha; phosphatidylinositol 4-kinase type II-alpha; EC 2.7.1.67
• Gene ID: 84095
• mRNA Refseq: NM_145501
• Protein Refseq: NP_663476
• UniProt ID: Q2TBE6