Recombinant Mouse Plcg1 Protein, Myc/DDK-tagged

• Cat.No.: Plcg1-4917M
• Product Overview: Purified recombinant protein of mouse full-length phospholipase C, gamma 1 (Plcg1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 150.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Plcg1 phospholipase C, gamma 1 [ Mus musculus (house mouse) ]
• Official Symbol: Plcg1
• Synonyms: PLCG1; phospholipase C, gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; PLC-gamma-1; phospholipase C-gamma-1; phosphoinositide phospholipase C-gamma-1; cell differentiation and embryonic development; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; Cded; Plc-1; Plcg-1; AI894140; Plc-gamma1
• Gene ID: 18803
• mRNA Refseq: NM_021280
• Protein Refseq: NP_067255
• UniProt ID: Q62077