Recombinant Mouse Plxna1 Protein, Myc/DDK-tagged
Cat.No. : | Plxna1-4948M |
Product Overview : | Purified recombinant protein of mouse full-length plexin A1 (Plxna1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 211.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Plxna1 plexin A1 [ Mus musculus (house mouse) ] |
Official Symbol : | Plxna1 |
Synonyms : | PLXNA1; plexin A1; plexin-A1; plex 1; plexin 1; plexin-1; NOV; Plxn1; PlexA1; mKIAA4053; 2600013D04Rik; KIAA4053 |
Gene ID : | 18844 |
mRNA Refseq : | NM_008881 |
Protein Refseq : | NP_032907 |
UniProt ID : | P70206 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionPLXNA1 plays a role in the formation of synapses, essential for effective neural communication.
PLXNA1 interacts with various signaling molecules, coordinating complex neural development processes.
Altered PLXNA1 activity is linked to neurodevelopmental disorders due to its role in neuronal guidance and synapse formation.
PLXNA1, a receptor in the plexin family, is crucial for neuronal development and pathway formation.
Targeting PLXNA1 offers potential for treating conditions related to neural development and connectivity.
It guides axon growth and direction, influencing the wiring of the nervous system.
Genetic mutations in PLXNA1 can disrupt neural pathways, affecting brain structure and function.
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