Recombinant Mouse Prag1 Protein, Myc/DDK-tagged
Cat.No. : | Prag1-5094M |
Product Overview : | Purified recombinant protein of mouse full-length PEAK1 related kinase activating pseudokinase 1 (Prag1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Catalytically inactive protein kinase that acts as a scaffold protein. Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth. Promotes Src family kinase (SFK) signaling by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism. Acts as a critical coactivator of Notch signaling. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 148.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Prag1 PEAK1 related kinase activating pseudokinase 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Prag1 |
Synonyms : | Prag1; PEAK1 related kinase activating pseudokinase 1; NA; NACK; Sgk223; D8Ertd82; D8Ertd82e; mFLJ00269; 9830148H23; inactive tyrosine-protein kinase PRAG1; notch activation complex kinase; pragmin; sugen kinase 223; tyrosine-protein kinase PRAG1; tyrosine-protein kinase SgK223; EC 2.7.10.2 |
Gene ID : | 244418 |
mRNA Refseq : | NM_172911 |
Protein Refseq : | NP_766499 |
UniProt ID : | Q571I4 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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