Recombinant Mouse Pten Protein, Myc/DDK-tagged

• Cat.No.: Pten-5216M
• Product Overview: Purified recombinant protein of mouse full-length phosphatase and tensin homolog (Pten), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a phosphatase with dual activity against phospholipids and proteins, and acts as a tumor-suppressor. The protein contains four structural domains, a PIP2-binding domain, a catalytic tensin-type phosphatase domain, a C2 tensin-type domain and a PDZ-binding domain. The protein belongs to the protein tyrosine phosphatase family. Deletion of this gene in mice contribute to tumorigenesis in multiple tissues.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 47.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pten phosphatase and tensin homolog [ Mus musculus (house mouse) ]
• Official Symbol: Pten
• Synonyms: PTEN; phosphatase and tensin homolog; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; mutated in multiple advanced cancers 1; TEP1; MMAC1; AI463227; 2310035O07Rik; A130070J02Rik; B430203M17Rik; MGC183880
• Gene ID: 19211
• mRNA Refseq: NM_008960
• Protein Refseq: NP_032986
• UniProt ID: O08586