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Recombinant Mouse PTK7 Protein, His and Myc tagged

Cat.No. : PTK7-13660M
Product Overview : Recombinant Mouse PTK7 Protein with His and Myc tag was expressed in E. coli.
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Description : Predicted to enable cell adhesion molecule binding activity. Acts upstream of or within several processes, including animal organ development; axis elongation; and morphogenesis of an epithelium. Located in cell-cell junction and plasma membrane. Is expressed in several structures, including alimentary system; nervous system; paraxial mesenchyme; reproductive system; and sensory organ. Orthologous to human PTK7 (protein tyrosine kinase 7 (inactive)).
Source : E. coli
Species : Mouse
Tag : His and Myc
Molecular Mass : 79 kDa
AA Sequence : AVDRLQDSGAFQCVARDNVTGEEVR STNASFNIKWIEAGPVVLKHPASEA EIQPQTQVTLRCHIDGHPRPTYQWF RDGTPLSDDQSTHTVSSRERNLTLR PASPEHSGLYSCCAHNAFGQACSSQ NFTLSVADESFARVVLAPQDVVVAR NEEAMFHCQFSAQPPPSLQWVFEDE TPITNRSRPPHLRRAVVFANGSLLL TQVRPRNAGVYRCIGQGQRGPPIVL EATLHLAEIEDMLPFEPRVFIAGDE ERVTCPAPQGLPTPSVWWEHAGVPL PAHGRVHQKGLELVFVTIAESDTGV YTCHASNLAGQRRQDVNITVATVPT WLRKPQDSQLEEGKPGYLHCLTQAT PKPTVIWYRNQMLISEDSRFEVSKN GTLRINSVEVYDGTLYRCVSSTPAG SIEAQARVQVLEKLKFTPPPQPQQC MEFDKEATVPCSATGREKPTVKWVR ADGSSLPEWVTDNAGTLHFARVTRD DAGNYTCIASNEPQGQIRAHVQLTV AVFITFKVEPERTTVYQGHTALLRC EAQGDPKPLIQWKGKDRILDPTKLG PRMHIFQNGSLVIHDVAPEDSGSYT CIAGNSCNIRHTEAPLLVVDKPVME DSEGPGSPPPYKMIQT
Endotoxin : < 1.0 EU/μg of the protein as determined by the LAL method.
Purity : > 90% by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Storage Buffer : Lyophilized from sterile 20mM Tris-HCl, 500mM NaCl, pH8.0.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Name : Ptk7 PTK7 protein tyrosine kinase 7 [ Mus musculus (house mouse) ]
Official Symbol : PTK7
Synonyms : PTK7; PTK7 protein tyrosine kinase 7; inactive tyrosine-protein kinase 7; protein chuzhoi; protein-tyrosine kinase 7; tyrosine-protein kinase-like 7; pseudo tyrosine kinase receptor 7; receptor tyrosine kinase-like protein; chz; mPTK7/CCK4; 8430404F20Rik;
Gene ID : 71461
mRNA Refseq : NM_175168
Protein Refseq : NP_780377

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Does PTK7 have specific extracellular domains? 12/30/2021

Yes, PTK7 possesses extracellular domains, including a Wnt co-receptor domain, suggesting involvement in Wnt signaling pathways.

In which cellular processes does PTK7 participate? 11/07/2021

PTK7 is involved in diverse processes, including cell proliferation, migration, tissue morphogenesis, and planar cell polarity.

Are there potential therapeutic applications for PTK7? 10/29/2021

PTK7 is being explored as a potential therapeutic target, particularly in cancer treatment and tissue regeneration.

What role does PTK7 play in planar cell polarity? 04/10/2020

PTK7 plays a pivotal role in planar cell polarity, contributing to the alignment of cells and tissues during development.

What is the full name of PTK7? 06/04/2019

PTK7 stands for Protein Tyrosine Kinase 7.

What kind of protein is PTK7? 07/24/2018

PTK7 is a transmembrane receptor protein with tyrosine kinase activity.

Is PTK7 implicated in any diseases? 09/19/2016

Altered expression of PTK7 has been associated with various cancers, including colorectal cancer.

Customer Reviews (3)

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09/09/2019

    We observed that results obtained with the product remained stable and reliable over long-term experiments.

    06/19/2019

      We appreciated that the product adhered to relevant regulatory standards, ensuring the ethical conduct of our experiments.

      02/12/2019

        The product's compliance with safety and ethical guidelines made it a responsible choice for our research endeavors.

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