| Description : |
Enables endopeptidase activity. Acts upstream of or within with a positive effect on regulation of blood pressure. Acts upstream of or within several processes, including drinking behavior; male gonad development; and regulation of systemic arterial blood pressure by renin-angiotensin. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and trunk. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (renin). |
| Source : |
HEK293 |
| Species : |
Mouse |
| Form : |
Lyophilized |
| Molecular Mass : |
43.2 kDa |
| Protein Length : |
402 |
| AA Sequence : |
MDRRRMPLWALLLLWSPCTFSLPTR TATFERIPLKKMPSVREILEERGVD MTRLSAEWGVFTKRPSLTNLTSPVV LTNYLNTQYYGEIGIGTPPQTFKVI FDTGSANLWVPSTKCSRLYLACGIH SLYESSDSSSYMENGSDFTIHYGSG RVKGFLSQDSVTVGGITVTQTFGEV TELPLIPFMLAKFDGVLGMGFPAQA VGGVTPVFDHILSQGVLKEEVFSVY YNRGSHLLGGEVVLGGSDPQHYQGN FHYVSISKTDSWQITMKGVSVGSST LLCEEGCAVVVDTGSSFISAPTSSL KLIMQALGAKEKRIEEYVVNCSQVP TLPDISFDLGGRAYTLSSTDYVLQY PNRRDKLCTLALHAMDIPPPTGPVW VLGATFIRKFYTEFDRHNNRIGFAL AR |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
