Recombinant Mouse Retreg1 Protein, Myc/DDK-tagged

• Cat.No.: Retreg1-5472M
• Product Overview: Purified recombinant protein of mouse full-length reticulophagy regulator 1 (Retreg1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes. Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins. Required for long-term survival of nociceptive and autonomic ganglion neurons.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 39 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Retreg1 reticulophagy regulator 1 [ Mus musculus (house mouse) ]
• Official Symbol: Retreg1
• Synonyms: Retreg1; reticulophagy regulator 1; Fam134; Fam134b; AU015349; Retreg1d; 1810015C04Rik; reticulophagy regulator 1; family with sequence similarity 134, member B; protein FAM134B; reticulophagy receptor 1; reticulophagy receptor Fam134b
• Gene ID: 66270
• mRNA Refseq: NM_025459
• Protein Refseq: NP_079735
• UniProt ID: Q8VE91