Recombinant Mouse Rhoa Protein, MYC/DDK-tagged

• Cat.No.: Rhoa-641M
• Product Overview: Purified recombinant protein of full-length mouse ras homolog family member A (Rhoa), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
• Molecular Mass: 22.2 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rhoa ras homolog family member A [ Mus musculus (house mouse) ]
• Official Symbol: Rhoa
• Synonyms: Rhoa; ras homolog family member A; Arha; Arha1; Arha2; transforming protein RhoA; aplysia ras-related homolog A; ras homolog gene family, member A; EC 3.6.5.2
• Gene ID: 11848
• mRNA Refseq: NM_016802
• Protein Refseq: NP_058082
• UniProt ID: Q9QUI0